Cargando…

TERT alleviates irradiation-induced late rectal injury by reducing hypoxia-induced ROS levels through the activation of NF-κB and autophagy

The hypoxic microenvironment which is present following irradiation has been proven to promote radiation-induced injury to normal tissues. Previous studies have demonstrated that telomerase reverse transcriptase (TERT) is regulated by hypoxia, and that it plays a protective role in the process of wo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Qi, Sun, Yong, Lv, Yuefeng, Le, Ziyu, Xin, Yuhu, Zhang, Ping, Liu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990283/ https://www.ncbi.nlm.nih.gov/pubmed/27431814 http://dx.doi.org/10.3892/ijmm.2016.2673

Ejemplares similares

CpG-Oligodeoxynucleotides Alleviate Tert-Butyl Hydroperoxide-Induced Macrophage Apoptosis by Regulating Mitochondrial Function and Suppressing ROS Production
por: Qu, Yibai, et al.
Publicado: (2020)

Diosmetin alleviates hypoxia-induced myocardial apoptosis by inducing autophagy through AMPK activation
por: Si, Qijun, et al.
Publicado: (2020)

Autophagy Induced by Micheliolide Alleviates Acute Irradiation-Induced Intestinal Injury via Inhibition of the NLRP3 Inflammasome
por: Wu, Dong-ming, et al.
Publicado: (2022)

Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells
por: Qin, Wenjie, et al.
Publicado: (2015)

Cardiac Shock Wave Therapy Alleviates Hypoxia/Reoxygenation-Induced Myocardial Necroptosis by Modulating Autophagy
por: Qiu, Quan, et al.
Publicado: (2021)

Melatonin-Mediated Suppression of mtROS-JNK-FOXO1 Pathway Alleviates Hypoxia-Induced Apoptosis in Porcine Granulosa Cells
por: Zhang, Xuan, et al.
Publicado: (2023)

Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS–AMPK–mTOR axis
por: Li, Ming-yong, et al.
Publicado: (2019)

URI1 suppresses irradiation-induced reactive oxygen species (ROS) by activating autophagy in hepatocellular carcinoma cells
por: Xu, Yue, et al.
Publicado: (2021)

Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis
por: Chen, Haitao, et al.
Publicado: (2023)

Do Autophagy Enhancers/ROS Scavengers Alleviate Consequences of Mild Mitochondrial Dysfunction Induced in Neuronal-Derived Cells?
por: Odeya, Damri, et al.
Publicado: (2021)

Hypoxia induces autophagy in cardiomyocytes via a hypoxia-inducible factor 1-dependent mechanism
por: GUI, LAN, et al.
Publicado: (2016)

Hypoxia Induced NF-κB
por: D’Ignazio, Laura, et al.
Publicado: (2016)

Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
por: Ma, Tiffany S, et al.
Publicado: (2023)

Melatonin Alleviates Hypoxia-Induced Apoptosis of Granulosa Cells by Reducing ROS and Activating MTNR1B–PKA–Caspase8/9 Pathway
por: Tao, Jing-Li, et al.
Publicado: (2021)

Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord
por: Huang, Yulin, et al.
Publicado: (2022)

Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways
por: Zhang, Guo-Yu, et al.
Publicado: (2018)

Autophagy alleviates amiodarone-induced hepatotoxicity
por: Wandrer, Franziska, et al.
Publicado: (2020)

Metformin alleviates irradiation-induced intestinal injury by activation of FXR in intestinal epithelia
por: Yang, Jing-Yu, et al.
Publicado: (2022)

ROS-induced oxidative stress in plant cryopreservation: occurrence and alleviation
por: Ren, Li, et al.
Publicado: (2021)

Oxalate-induced apoptosis through ERS-ROS–NF-κB signalling pathway in renal tubular epithelial cell
por: Ming, Shaoxiong, et al.
Publicado: (2022)

5-O-Demethylnobiletin Alleviates CCl(4)-Induced Acute Liver Injury by Equilibrating ROS-Mediated Apoptosis and Autophagy Induction
por: Chang, Sukkum Ngullie, et al.
Publicado: (2021)

Luteolin decreases the UVA-induced autophagy of human skin fibroblasts by scavenging ROS
por: Yan, Miaomiao, et al.
Publicado: (2016)

Pyrocatechol Alleviates Cisplatin-Induced Acute Kidney Injury by Inhibiting ROS Production
por: Xie, Xuexia, et al.
Publicado: (2022)

Curcumin activates autophagy and attenuates high glucose-induced apoptosis in HUVECs through the ROS/NF-κB signaling pathway
por: Jin, Qi-Hui, et al.
Publicado: (2022)

ARMS-NF-κB signaling regulates intracellular ROS to induce autophagy-associated cell death upon oxidative stress
por: Liao, Yi-Hua, et al.
Publicado: (2023)

Diphenyl Diselenide Alleviates Tert-Butyl Hydrogen Peroxide-Induced Oxidative Stress and Lipopolysaccharide-Induced Inflammation in Rat Glomerular Mesangial Cells
por: Wang, Xing, et al.
Publicado: (2022)

Hypoxia-Induced ROS Contribute to Myoblast Pyroptosis during Obstructive Sleep Apnea via the NF-κB/HIF-1α Signaling Pathway
por: Yu, Li-Ming, et al.
Publicado: (2019)

Baicalin attenuates liver hypoxia/reoxygenation injury by inducing autophagy
por: Liu, Feng, et al.
Publicado: (2018)

CRIF1 overexpression facilitates tumor growth and metastasis through inducing ROS/NFκB pathway in hepatocellular carcinoma
por: Chang, Hulin, et al.
Publicado: (2020)

Cilostazol alleviate nicotine induced cardiomyocytes hypertrophy through modulation of autophagy by CTSB/ROS/p38MAPK/JNK feedback loop
por: Wang, Shu-ya, et al.
Publicado: (2020)

Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways
por: Ji, Lu, et al.
Publicado: (2017)

Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells
por: Liu, Ting, et al.
Publicado: (2015)

Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells
por: Hou, J, et al.
Publicado: (2013)

Taurine Alleviates Cadmium-Induced Hepatotoxicity by Regulating Autophagy Flux
por: Duan, Yuntian, et al.
Publicado: (2023)

N-Acetylcysteine, an ROS Inhibitor, Alleviates the Pathophysiology of Hyperthyroidism-Induced Cardiomyopathy via the ROS/Ca(2+) Pathway
por: Bao, Mengni, et al.
Publicado: (2022)

Low-dose dexamethasone affects osteoblast viability by inducing autophagy via intracellular ROS
por: Zhang, Shaokun, et al.
Publicado: (2018)

Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation
por: Yuan, Yong-Liang, et al.
Publicado: (2019)

Compound 275# Induces Mitochondria-Mediated Apoptosis and Autophagy Initiation in Colorectal Cancer Cells through an Accumulation of Intracellular ROS
por: Yang, Dong-Lin, et al.
Publicado: (2023)

Genetic Variants of the TERT Gene, Telomere Length, and Circulating TERT as Prognostic Markers in Rectal Cancer Patients
por: Rampazzo, Enrica, et al.
Publicado: (2020)

Quercetin alleviates high glucose-induced Schwann cell damage by autophagy
por: Qu, Ling, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jvd1cttijpt07rpphge3jc5qdi