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The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats
Sepsis-induced acute kidney injury (AKI) represents a major cause of mortality in intensive care units. Sivelestat, a selective inhibitor of neutrophil elastase (NE), can attenuate sepsis-related acute lung injury. However, whether sivelestat can preserve kidney function during sepsis remains unclea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990314/ https://www.ncbi.nlm.nih.gov/pubmed/27430552 http://dx.doi.org/10.3892/ijmm.2016.2665 |