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Discretization of Gene Expression Data Unmasks Molecular Subgroups Recurring in Different Human Cancer Types

Despite the individually different molecular alterations in tumors, the malignancy associated biological traits are strikingly similar. Results of a previous study using renal cell carcinoma (RCC) as a model pointed towards cancer-related features, which could be visualized as three groups by microa...

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Detalles Bibliográficos
Autores principales: Beleut, Manfred, Soeldner, Robert, Egorov, Mark, Guenther, Rolf, Dehler, Silvia, Morys-Wortmann, Corinna, Moch, Holger, Henco, Karsten, Schraml, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990327/
https://www.ncbi.nlm.nih.gov/pubmed/27537329
http://dx.doi.org/10.1371/journal.pone.0161514