Cargando…

A Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin Receptor

Cervical cancer is one of the leading causes of cancer death in women worldwide. The causative agents of cervical cancers, high-risk human papillomaviruses (HPVs), cause cancer through the action of two oncoproteins, E6 and E7. The E6 oncoprotein cooperates with an E3 ubiquitin ligase (UBE3A) to tar...

Descripción completa

Detalles Bibliográficos
Autores principales: Padash Barmchi, Mojgan, Gilbert, Mary, Thomas, Miranda, Banks, Lawrence, Zhang, Bing, Auld, Vanessa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990329/
https://www.ncbi.nlm.nih.gov/pubmed/27537218
http://dx.doi.org/10.1371/journal.ppat.1005789