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Molecular Models of STAT5A Tetramers Complexed to DNA Predict Relative Genome-Wide Frequencies of the Spacing between the Two Dimer Binding Motifs of the Tetramer Binding Sites

STAT proteins bind DNA as dimers and tetramers to control cellular development, differentiation, survival, and expansion. The tetramer binding sites are comprised of two dimer-binding sites repeated in tandem. The genome-wide distribution of the spacings between the dimer binding sites shows a disti...

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Detalles Bibliográficos
Autores principales: Sathyanarayana, Bangalore K., Li, Peng, Lin, Jian-Xin, Leonard, Warren J., Lee, Byungkook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990345/
https://www.ncbi.nlm.nih.gov/pubmed/27537504
http://dx.doi.org/10.1371/journal.pone.0160339