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A Novel Ex Vivo Method for Visualizing Live-Cell Calcium Response Behavior in Intact Human Tumors

The functional impact of intratumoral heterogeneity has been difficult to assess in the absence of a means to interrogate dynamic, live-cell biochemical events in the native tissue context of a human tumor. Conventional histological methods can reveal morphology and static biomarker expression patte...

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Detalles Bibliográficos
Autores principales: Koh, James, Hogue, Joyce A., Sosa, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990350/
https://www.ncbi.nlm.nih.gov/pubmed/27537691
http://dx.doi.org/10.1371/journal.pone.0161134