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Aging impairs osteoblast differentiation of mesenchymal stem cells grown on titanium by favoring adipogenesis

Aging negatively affects bone/titanium implant interactions. Our hypothesis is that the unbalance between osteogenesis and adipogenesis induced by aging may be involved in this phenomenon. OBJECTIVE: We investigated the osteoblast and adipocyte differentiation of mesenchymal stem cells (MSCs) from y...

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Detalles Bibliográficos
Autores principales: ABUNA, Rodrigo Paolo Flores, STRINGHETTA-GARCIA, Camila Tami, FIORI, Leonardo Pimentel, DORNELLES, Rita Cassia Menegati, ROSA, Adalberto Luiz, BELOTI, Marcio Mateus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade De Odontologia De Bauru - USP 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990367/
https://www.ncbi.nlm.nih.gov/pubmed/27556209
http://dx.doi.org/10.1590/1678-775720160037