Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in breast cancer patients treated with paclitaxel and docetaxel

BACKGROUND: Interindividual variability of pharmacogenetics may account for unpredictable neurotoxicities of taxanes. METHODS: From March 2011 to June 2015, female patients with operable breast cancer who had received docetaxel- or paclitaxel-containing adjuvant chemotherapy were included in this st...

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Detalles Bibliográficos
Autores principales: Kus, Tulay, Aktas, Gokmen, Kalender, Mehmet Emin, Demiryurek, Abdullah Tuncay, Ulasli, Mustafa, Oztuzcu, Serdar, Sevinc, Alper, Kul, Seval, Camci, Celaletdin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990373/
https://www.ncbi.nlm.nih.gov/pubmed/27574448
http://dx.doi.org/10.2147/OTT.S106574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990373/
https://www.ncbi.nlm.nih.gov/pubmed/27574448
http://dx.doi.org/10.2147/OTT.S106574

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