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Tbx16 regulates hox gene activation in mesodermal progenitor cells

The transcription factor T-box 16 (Tbx16/Spadetail) is an essential regulator of paraxial mesoderm development in zebrafish (Danio rerio). Mesodermal progenitor cells (MPCs) fail to differentiate into trunk somites in tbx16 mutants and instead accumulate within the tailbud in an immature state. The...

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Detalles Bibliográficos
Autores principales: Payumo, Alexander Y., McQuade, Lindsey E., Walker, Whitney J., Yamazoe, Sayumi, Chen, James K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990471/
https://www.ncbi.nlm.nih.gov/pubmed/27376691
http://dx.doi.org/10.1038/nchembio.2124