ZDHHC7-Mediated S-Palmitoylation of Scribble Regulates Cell Polarity

Scribble (SCRIB) is a tumor suppressor protein, playing critical roles in establishing and maintaining epithelial cell polarity. Paradoxically, SCRIB is frequently amplified in human cancers, however, fails to localize properly to cell-cell junctions, suggesting that mislocalization of SCRIB contrib...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Baoen, Zheng, Baohui, DeRan, Micael, Jarugumilli, Gopala K., Fu, Jianjun, Brooks, Yang S., Wu, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990496/
https://www.ncbi.nlm.nih.gov/pubmed/27380321
http://dx.doi.org/10.1038/nchembio.2119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990496/
https://www.ncbi.nlm.nih.gov/pubmed/27380321
http://dx.doi.org/10.1038/nchembio.2119

Ejemplares similares