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ZDHHC7-Mediated S-Palmitoylation of Scribble Regulates Cell Polarity
Scribble (SCRIB) is a tumor suppressor protein, playing critical roles in establishing and maintaining epithelial cell polarity. Paradoxically, SCRIB is frequently amplified in human cancers, however, fails to localize properly to cell-cell junctions, suggesting that mislocalization of SCRIB contrib...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990496/ https://www.ncbi.nlm.nih.gov/pubmed/27380321 http://dx.doi.org/10.1038/nchembio.2119 |