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Modeling the Pro-inflammatory Tumor Microenvironment in Acute Lymphoblastic Leukemia Predicts a Breakdown of Hematopoietic-Mesenchymal Communication Networks

Lineage fate decisions of hematopoietic cells depend on intrinsic factors and extrinsic signals provided by the bone marrow microenvironment, where they reside. Abnormalities in composition and function of hematopoietic niches have been proposed as key contributors of acute lymphoblastic leukemia (A...

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Detalles Bibliográficos
Autores principales: Enciso, Jennifer, Mayani, Hector, Mendoza, Luis, Pelayo, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990565/
https://www.ncbi.nlm.nih.gov/pubmed/27594840
http://dx.doi.org/10.3389/fphys.2016.00349