Cargando…
Analysis of cancer genomes reveals basic features of human aging and its role in cancer development
Somatic mutations have long been implicated in aging and disease, but their impact on fitness and function is difficult to assess. Here by analysing human cancer genomes we identify mutational patterns associated with aging. Our analyses suggest that age-associated mutation load and burden double ap...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990632/ https://www.ncbi.nlm.nih.gov/pubmed/27515585 http://dx.doi.org/10.1038/ncomms12157 |