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Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?

Challenges posed by complex diseases such as cancer, chronic viral infections, neurodegenerative disorders and many others have forced researchers to think beyond classic small molecule drugs, exploring new therapeutic strategies such as therapy with RNAi, CRISPR/Cas9 or antibody therapies as single...

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Detalles Bibliográficos
Autores principales: Marschall, Andrea L.J., Dübel, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990636/
https://www.ncbi.nlm.nih.gov/pubmed/27570612
http://dx.doi.org/10.1016/j.csbj.2016.07.003