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Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

Activation of purinergic receptors in the spinal cord by extracellular ATP is essential for neuropathic hypersensitivity after peripheral nerve injury (PNI). However, the cell type responsible for releasing ATP within the spinal cord after PNI is unknown. Here we show that PNI increases expression o...

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Detalles Bibliográficos
Autores principales: Masuda, Takahiro, Ozono, Yui, Mikuriya, Satsuki, Kohro, Yuta, Tozaki-Saitoh, Hidetoshi, Iwatsuki, Ken, Uneyama, Hisayuki, Ichikawa, Reiko, Salter, Michael W., Tsuda, Makoto, Inoue, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990655/
https://www.ncbi.nlm.nih.gov/pubmed/27515581
http://dx.doi.org/10.1038/ncomms12529