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Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain
Activation of purinergic receptors in the spinal cord by extracellular ATP is essential for neuropathic hypersensitivity after peripheral nerve injury (PNI). However, the cell type responsible for releasing ATP within the spinal cord after PNI is unknown. Here we show that PNI increases expression o...
Autores principales: | Masuda, Takahiro, Ozono, Yui, Mikuriya, Satsuki, Kohro, Yuta, Tozaki-Saitoh, Hidetoshi, Iwatsuki, Ken, Uneyama, Hisayuki, Ichikawa, Reiko, Salter, Michael W., Tsuda, Makoto, Inoue, Kazuhide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990655/ https://www.ncbi.nlm.nih.gov/pubmed/27515581 http://dx.doi.org/10.1038/ncomms12529 |
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