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Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
(Hetero)Aryl amines, an important class of organic molecules in medicinal chemistry, are most commonly synthesized from anilines, which are in turn synthesized by hydrogenation of nitroarenes. Amine synthesis directly from nitroarenes is attractive due to improved step economy and functional group c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990657/ https://www.ncbi.nlm.nih.gov/pubmed/27515391 http://dx.doi.org/10.1038/ncomms12494 |