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Epigenetic and Glucocorticoid Receptor-Mediated Regulation of Glutathione Peroxidase 3 in Lung Cancer Cells

Glutathione peroxidase 3 (GPx3), an antioxidant enzyme, acts as a modulator of redox signaling, has immunomodulatory function, and catalyzes the detoxification of reactive oxygen species (ROS). GPx3 has been identified as a tumor suppressor in many cancers. Although hyper-methylation of the GPx3 pro...

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Detalles Bibliográficos
Autores principales: An, Byung Chull, Jung, Nak-Kyun, Park, Chun Young, Oh, In-Jae, Choi, Yoo-Duk, Park, Jae-Il, Lee, Seung-won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990756/
https://www.ncbi.nlm.nih.gov/pubmed/27484907
http://dx.doi.org/10.14348/molcells.2016.0164