CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data

BACKGROUND: Copy number alteration is a main genetic structural variation that plays an important role in tumor initialization and progression. Accurate detection of copy number alterations is necessary for discovering cancer-causing genes. Whole-exome sequencing has become a widely used technology...

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Detalles Bibliográficos
Autores principales: Yu, Zhenhua, Li, Ao, Wang, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990858/
https://www.ncbi.nlm.nih.gov/pubmed/27538789
http://dx.doi.org/10.1186/s12859-016-1174-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990858/
https://www.ncbi.nlm.nih.gov/pubmed/27538789
http://dx.doi.org/10.1186/s12859-016-1174-7

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