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Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis

Inflammatory bowel disease (IBD) arises by unknown environmental triggers in genetically susceptible individuals. Epigenetic regulation of gene expression may integrate internal and external influences and may thereby modulate disease susceptibility. Epigenetic modification may also affect the germ-...

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Detalles Bibliográficos
Autores principales: Tschurtschenthaler, Markus, Kachroo, Priyadarshini, Heinsen, Femke-Anouska, Adolph, Timon Erik, Rühlemann, Malte Christoph, Klughammer, Johanna, Offner, Felix Albert, Ammerpohl, Ole, Krueger, Felix, Smallwood, Sébastien, Szymczak, Silke, Kaser, Arthur, Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990911/
https://www.ncbi.nlm.nih.gov/pubmed/27538787
http://dx.doi.org/10.1038/srep31640