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Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis
Inflammatory bowel disease (IBD) arises by unknown environmental triggers in genetically susceptible individuals. Epigenetic regulation of gene expression may integrate internal and external influences and may thereby modulate disease susceptibility. Epigenetic modification may also affect the germ-...
Autores principales: | Tschurtschenthaler, Markus, Kachroo, Priyadarshini, Heinsen, Femke-Anouska, Adolph, Timon Erik, Rühlemann, Malte Christoph, Klughammer, Johanna, Offner, Felix Albert, Ammerpohl, Ole, Krueger, Felix, Smallwood, Sébastien, Szymczak, Silke, Kaser, Arthur, Franke, Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990911/ https://www.ncbi.nlm.nih.gov/pubmed/27538787 http://dx.doi.org/10.1038/srep31640 |
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