Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons

Synapse formation and plasticity depend on nuclear transcription and site-specific protein targeting, but the molecular mechanisms that coordinate these steps have not been well defined. The MEN1 tumor suppressor gene, which encodes the protein menin, is known to induce synapse formation and plastic...

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Detalles Bibliográficos
Autores principales: Getz, Angela M., Visser, Frank, Bell, Erin M., Xu, Fenglian, Flynn, Nichole M., Zaidi, Wali, Syed, Naweed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990912/
https://www.ncbi.nlm.nih.gov/pubmed/27538741
http://dx.doi.org/10.1038/srep31779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990912/
https://www.ncbi.nlm.nih.gov/pubmed/27538741
http://dx.doi.org/10.1038/srep31779

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