Cargando…

hCG-induced Sprouty2 mediates amphiregulin-stimulated COX-2/PGE2 up-regulation in human granulosa cells: a potential mechanism for the OHSS

Sprouty2 (SPRY2) is an important intracellular regulator for epidermal growth factor receptor (EGFR)-mediated ERK1/2 signaling. In human granulosa cells, although SPRY2 is expressed, its regulation and function remains complete unknown and must be defined. Our previous study has shown that human cho...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Jung-Chien, Fang, Lanlan, Chang, Hsun-Ming, Sun, Ying-Pu, Leung, Peter C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990972/
https://www.ncbi.nlm.nih.gov/pubmed/27539669
http://dx.doi.org/10.1038/srep31675