Organotypic culture in three dimensions prevents radiation-induced transformation in human lung epithelial cells

The effects of radiation in two-dimensional (2D) cell culture conditions may not recapitulate tissue responses as modeled in three-dimensional (3D) organotypic culture. In this study, we determined if the frequency of radiation-induced transformation and cancer progression differed in 3D compared to...

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Detalles Bibliográficos
Autores principales: El-Ashmawy, Mariam, Coquelin, Melissa, Luitel, Krishna, Batten, Kimberly, Shay, Jerry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990973/
https://www.ncbi.nlm.nih.gov/pubmed/27539227
http://dx.doi.org/10.1038/srep31669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990973/
https://www.ncbi.nlm.nih.gov/pubmed/27539227
http://dx.doi.org/10.1038/srep31669

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