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Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome

Understanding the role of autophagy in cancer has been limited by the inability to measure this dynamic process in formalin-fixed tissue. We considered that 3-dimensional models including ex vivo tumor, such as we have developed for studying mesothelioma, would provide valuable insights. Using these...

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Detalles Bibliográficos
Autores principales: Follo, Carlo, Barbone, Dario, Richards, William G., Bueno, Raphael, Broaddus, V. Courtney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990992/
https://www.ncbi.nlm.nih.gov/pubmed/27097020
http://dx.doi.org/10.1080/15548627.2016.1173799