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Revisiting autophagy addiction of tumor cells

Inhibition of autophagy has been widely explored as a potential therapeutic intervention for cancer. Different factors such as tumor origin, tumor stage and genetic background can define a tumor's response to autophagy modulation. Notably, tumors with oncogenic mutations in KRAS were reported t...

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Detalles Bibliográficos
Autores principales: Nyfeler, Beat, Eng, Christina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990994/
https://www.ncbi.nlm.nih.gov/pubmed/27097231
http://dx.doi.org/10.1080/15548627.2016.1170265