The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing

BACKGROUND: After viral infection and the stimulation of some pattern-recognition receptors, TANK-binding kinase I (TBK1) is activated by K63-linked polyubiquitination followed by trans-autophosphorylation. While the activated TBK1 induces type I interferon production by phosphorylating the transcri...

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Detalles Bibliográficos
Autores principales: Pourcelot, Marie, Zemirli, Naima, Silva Da Costa, Leandro, Loyant, Roxane, Garcin, Dominique, Vitour, Damien, Munitic, Ivana, Vazquez, Aimé, Arnoult, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991008/
https://www.ncbi.nlm.nih.gov/pubmed/27538435
http://dx.doi.org/10.1186/s12915-016-0292-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991008/
https://www.ncbi.nlm.nih.gov/pubmed/27538435
http://dx.doi.org/10.1186/s12915-016-0292-z

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