Cargando…
The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing
BACKGROUND: After viral infection and the stimulation of some pattern-recognition receptors, TANK-binding kinase I (TBK1) is activated by K63-linked polyubiquitination followed by trans-autophosphorylation. While the activated TBK1 induces type I interferon production by phosphorylating the transcri...
Autores principales: | Pourcelot, Marie, Zemirli, Naima, Silva Da Costa, Leandro, Loyant, Roxane, Garcin, Dominique, Vitour, Damien, Munitic, Ivana, Vazquez, Aimé, Arnoult, Damien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991008/ https://www.ncbi.nlm.nih.gov/pubmed/27538435 http://dx.doi.org/10.1186/s12915-016-0292-z |
Ejemplares similares
-
The E3 ubiquitin ligase RNF121 is a positive regulator of NF-κB activation
por: Zemirli, Naima, et al.
Publicado: (2014) -
MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors
por: Castanier, Céline, et al.
Publicado: (2012) -
The Role of Optineurin in Antiviral Type I Interferon Production
por: Outlioua, Ahmed, et al.
Publicado: (2018) -
Traffic through the Golgi apparatus
por: Pelham, Hugh R.B.
Publicado: (2001) -
AN OBSERVATION ON THE FUNCTIONING OF THE GOLGI APPARATUS
por: Mollenhauer, Hilton H., et al.
Publicado: (1963)