Investigating the Molecular Basis of PPCD3: Characterization of ZEB1 Regulation of COL4A3 Expression

PURPOSE: To investigate the role of the zinc finger e-box binding homeobox 1 (ZEB1) transcription factor in posterior polymorphous corneal dystrophy 3 by demonstrating its ability to regulate type IV collagen gene transcription via binding to putative E2 box motifs. METHODS: Putative E2 box motifs w...

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Detalles Bibliográficos
Autores principales: Chung, Duk-Won D., Frausto, Ricardo F., Chiu, Stephan, Lin, Benjamin R., Aldave, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991021/
https://www.ncbi.nlm.nih.gov/pubmed/27537263
http://dx.doi.org/10.1167/iovs.16-19533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991021/
https://www.ncbi.nlm.nih.gov/pubmed/27537263
http://dx.doi.org/10.1167/iovs.16-19533

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