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Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma
BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive, fatal, childhood tumors that arise in the brainstem. DIPGs have no effective treatment, and their location and diffuse nature render them inoperable. Radiation therapy remains the only standard of care for this devastating...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991074/ https://www.ncbi.nlm.nih.gov/pubmed/27538997 http://dx.doi.org/10.1186/s12885-016-2690-6 |