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Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive, fatal, childhood tumors that arise in the brainstem. DIPGs have no effective treatment, and their location and diffuse nature render them inoperable. Radiation therapy remains the only standard of care for this devastating...

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Detalles Bibliográficos
Autores principales:	Amani, Vladimir, Prince, Eric W, Alimova, Irina, Balakrishnan, Ilango, Birks, Diane, Donson, Andrew M., Harris, Peter, Levy, Jean M. Mulcahy, Handler, Michael, Foreman, Nicholas K., Venkataraman, Sujatha, Vibhakar, Rajeev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991074/ https://www.ncbi.nlm.nih.gov/pubmed/27538997 http://dx.doi.org/10.1186/s12885-016-2690-6

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