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BCL9L expression in pancreatic neoplasia with a focus on SPN: a possible explanation for the enigma of the benign neoplasia

BACKGROUND: Solid pseudopapillary neoplasms of the pancreas (SPN) are rare tumors affecting mainly women. They show an activating mutation in CTNNB1, the gene for β-catenin, and consequently an overactivation of the Wnt/β-catenin pathway. This signaling pathway is implied in the pathogenesis of vari...

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Detalles Bibliográficos
Autores principales: Hallas, Cora, Phillipp, Julia, Domanowsky, Lukas, Kah, Bettina, Tiemann, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991076/
https://www.ncbi.nlm.nih.gov/pubmed/27539223
http://dx.doi.org/10.1186/s12885-016-2707-1