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In vivo functional analysis of Drosophila Robo1 immunoglobulin-like domains

BACKGROUND: In animals with bilateral symmetry, midline crossing of axons in the developing central nervous system is regulated by Slit ligands and their neuronal Roundabout (Robo) receptors. Multiple structural domains are present in an evolutionarily conserved arrangement in Robo family proteins,...

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Detalles Bibliográficos
Autores principales: Reichert, Marie C., Brown, Haley E., Evans, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991095/
https://www.ncbi.nlm.nih.gov/pubmed/27539083
http://dx.doi.org/10.1186/s13064-016-0071-0