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Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice
BACKGROUND: VE-cadherin is the chief constituent of endothelial adherens junctions. However, the role of VE-cadherin in the pathogenesis of cerebrovascular diseases including brain ischemia has not yet been investigated. METHODS: VE-cadherin heterozygous (VEC(+/-)) mice and wildtype controls were su...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991103/ https://www.ncbi.nlm.nih.gov/pubmed/27538712 http://dx.doi.org/10.1186/s12883-016-0670-8 |