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Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice

BACKGROUND: VE-cadherin is the chief constituent of endothelial adherens junctions. However, the role of VE-cadherin in the pathogenesis of cerebrovascular diseases including brain ischemia has not yet been investigated. METHODS: VE-cadherin heterozygous (VEC(+/-)) mice and wildtype controls were su...

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Detalles Bibliográficos
Autores principales:	Gertz, Karen, Kronenberg, Golo, Uhlemann, Ria, Prinz, Vincent, Marquina, Ruben, Corada, Monica, Dejana, Elisabetta, Endres, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991103/ https://www.ncbi.nlm.nih.gov/pubmed/27538712 http://dx.doi.org/10.1186/s12883-016-0670-8

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