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Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency

Although common variable immunodeficiency (CVID) has long been considered as a group of primary Ab deficiencies, growing experimental data now suggest a global disruption of the entire adaptive immune response in a segment of patients. Oligoclonality of the TCR repertoire was previously demonstrated...

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Detalles Bibliográficos
Autores principales: Wong, Gabriel K., Millar, David, Penny, Sarah, Heather, James M., Mistry, Punam, Buettner, Nico, Bryon, Jane, Huissoon, Aarnoud P., Cobbold, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991247/
https://www.ncbi.nlm.nih.gov/pubmed/27481850
http://dx.doi.org/10.4049/jimmunol.1600526