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Small‐Molecule and Peptide Inhibitors of the Pro‐Survival Protein Mcl‐1

The ability of protein–protein interactions to regulate cellular processes in both beneficial and detrimental ways has made them obvious drug targets. The Bcl‐2 family of proteins undergo a series of protein–protein interactions which regulate the intrinsic cell‐death pathway. The pro‐survival membe...

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Detalles Bibliográficos
Autores principales: Beekman, Andrew M., Howell, Lesley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991272/
https://www.ncbi.nlm.nih.gov/pubmed/26696548
http://dx.doi.org/10.1002/cmdc.201500497