Systematic Comparisons of Formulations of Linear Oligolysine Peptides with siRNA and Plasmid DNA

The effects of lysine peptide lengths on DNA and siRNA packaging and delivery were studied using four linear oligolysine peptides with 8 (K8), 16 (K16), 24 (K24) and 32 (K32) lysines. Oligolysine peptides with 16 lysines or longer were effective for stable monodisperse particle formation and optimal...

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Detalles Bibliográficos
Autores principales: Kwok, Albert, McCarthy, David, Hart, Stephen L., Tagalakis, Aristides D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991294/
https://www.ncbi.nlm.nih.gov/pubmed/26684657
http://dx.doi.org/10.1111/cbdd.12709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991294/
https://www.ncbi.nlm.nih.gov/pubmed/26684657
http://dx.doi.org/10.1111/cbdd.12709

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