BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

BAF180 (also called PBRM1), a subunit of the SWI/SNF complex, plays critical roles in the regulation of chromatin remodeling and gene transcription, and is frequently mutated in several human cancers. However, the role of mammalian BAF180 in tumor suppression and tissue maintenance in vivo remains l...

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Detalles Bibliográficos
Autores principales: Lee, Hyemin, Dai, Fangyan, Zhuang, Li, Xiao, Zhen-Dong, Kim, Jongchan, Zhang, Yilei, Ma, Li, You, M. James, Wang, Zhong, Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991371/
https://www.ncbi.nlm.nih.gov/pubmed/26992241
http://dx.doi.org/10.18632/oncotarget.8102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991371/
https://www.ncbi.nlm.nih.gov/pubmed/26992241
http://dx.doi.org/10.18632/oncotarget.8102

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