Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans

DAF-16, the C. elegans FOXO transcription factor, is an important determinant in aging and longevity. In this work, we manually curated FOXODB http://lyh.pkmu.cn/foxodb/, a database of FOXO direct targets. It now covers 208 genes. Bioinformatics analysis on 109 DAF-16 direct targets in C. elegans fo...

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Detalles Bibliográficos
Autores principales: Li, Yan-Hui, Zhang, Gai-Gai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991374/
https://www.ncbi.nlm.nih.gov/pubmed/27027346
http://dx.doi.org/10.18632/oncotarget.8313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991374/
https://www.ncbi.nlm.nih.gov/pubmed/27027346
http://dx.doi.org/10.18632/oncotarget.8313

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