CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4(+) T cell differentiation

Treatment targeting CD226 can ameliorate experimental autoimmune encephalomyelitis (EAE), the widely accepted model of MS. However, the mechanisms still need to be elucidated. Here we showed that CD226 blockage by anti-CD226 blocking mAb LeoA1 efficiently promoted IL-10 production in human periphera...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Rong, Zeng, Hanyu, Zhang, Yun, Chen, Kun, Zhang, Chunmei, Song, Chaojun, Fang, Liang, Xu, Zhuwei, Yang, Kun, Jin, Boquan, Wang, Qintao, Chen, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991380/
https://www.ncbi.nlm.nih.gov/pubmed/26942885
http://dx.doi.org/10.18632/oncotarget.7834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991380/
https://www.ncbi.nlm.nih.gov/pubmed/26942885
http://dx.doi.org/10.18632/oncotarget.7834

Ejemplares similares