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Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

ErbB3, a member of the ErbB family receptors, has a key role in the development and progression of several cancers, including non-small cell lung cancer (NSCLC), and in the establishment of resistance to therapies, leading to the development of anti-ErbB3 therapies. In this study we demonstrated, in...

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Detalles Bibliográficos
Autores principales: Ciardiello, Chiara, Roca, Maria Serena, Noto, Alessia, Bruzzese, Francesca, Moccia, Tania, Vitagliano, Carlo, Gennaro, Elena Di, Ciliberto, Gennaro, Roscilli, Giuseppe, Aurisicchio, Luigi, Marra, Emanuele, Mancini, Rita, Budillon, Alfredo, Leone, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991401/
https://www.ncbi.nlm.nih.gov/pubmed/26862736
http://dx.doi.org/10.18632/oncotarget.7195