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MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical cancer

The infection with high-risk human papillomavirus is linked to cervical cancer, nevertheless, the role of miRNAs regulated by HPV oncogenes in cancer progression remain largely unknown. Here, we knocked down endogenous E6/E7 in HPV16-positive CaSki cell lines, screened differences in miRNA expressio...

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Detalles Bibliográficos
Autores principales: Liu, Fei, Zhang, Shimeng, Zhao, Zhen, Mao, Xinru, Huang, Jinlan, Wu, Zixian, Zheng, Lei, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991410/
https://www.ncbi.nlm.nih.gov/pubmed/26910911
http://dx.doi.org/10.18632/oncotarget.7531