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Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas

Pediatric high-grade gliomas (pHGGs) are aggressive brain tumors affecting children, and outcomes have remained dismal, even with access to new multimodal therapies. In this study, we compared the miRNomes and transcriptomes of pediatric low- (pLGGs) and high-grade gliomas (pHGGs) using small RNA se...

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Detalles Bibliográficos
Autores principales: Liang, Muh-Lii, Hsieh, Tsung-Han, Ng, Kim-Hai, Tsai, Ya-Ni, Tsai, Cheng-Fong, Chao, Meng-En, Liu, Da-Jung, Chu, Shing-Shiung, Chen, Wan, Liu, Yun-Ru, Liu, Ren-Shyan, Lin, Shih-Chieh, Ho, Donald Ming-Tak, Wong, Tai-Tong, Yang, Muh-Hwa, Wang, Hsei-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991414/
https://www.ncbi.nlm.nih.gov/pubmed/26933822
http://dx.doi.org/10.18632/oncotarget.7736