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High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor

We employed a high-throughput drug library screening platform to identify novel agents affecting thyroid cancer cells. We used human thyroid cancer cell lines to screen a collection of approximately 5200 small molecules with biological and/or pharmacologial properties. Parallel primary screens yield...

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Detalles Bibliográficos
Autores principales: Zhang, Le, Yang, Zhaoying, Granieri, Letizia, Pasculescu, Adrian, Datti, Alessandro, Asa, Sylvia L., Xu, Zheli, Ezzat, Shereen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991430/
https://www.ncbi.nlm.nih.gov/pubmed/26942566
http://dx.doi.org/10.18632/oncotarget.7890