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Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1 gene during acquired multidrug resistant

PURPOSE: Pregnane x receptor (PXR) - activated overexpression of the multidrug resistance 1 (MDR1) gene is an important way for tumor cells to acquire drug resistance. However, the detailed mechanism still remains unclear. In the present study, we aimed to investigate whether protein arginine methyl...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Kong, Ah-Ng Tony, Ma, Zhiqiang, Liu, Haiyan, Liu, Pinghua, Xiao, Yu, Jiang, Xuehua, Wang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991450/
https://www.ncbi.nlm.nih.gov/pubmed/26934120
http://dx.doi.org/10.18632/oncotarget.7752