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Icmt inhibition exerts anti-angiogenic and anti-hyperpermeability activities impeding malignant pleural effusion

Small GTPases are pivotal regulators of several aspects of tumor progression. Their implication in angiogenesis, vascular permeability and tumor-associated inflammatory responses is relevant to the pathobiology of Malignant Pleural Effusion (MPE). Inhibition of isoprenylcysteine carboxylmethyltransf...

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Detalles Bibliográficos
Autores principales: Magkouta, Sophia, Pappas, Apostolos, Moschos, Charalampos, Vazakidou, Maria-Eleni, Psarra, Katherina, Kalomenidis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991451/
https://www.ncbi.nlm.nih.gov/pubmed/26959120
http://dx.doi.org/10.18632/oncotarget.7912