Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer

The dual specificity phosphatase Cdc25A is a key regulator of the cell cycle that promotes cell cycle progression by dephosphorylating and activating cyclin-dependent kinases. In response to genotoxicants, Cdc25A undergoes posttranslational modifications which contribute to its proteasome-mediated d...

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Detalles Bibliográficos
Autores principales: Lozada, Enerlyn M., Andrysik, Zdenek, Yin, Moying, Redilla, Nicholas, Rice, Kathryn, Stambrook, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991465/
https://www.ncbi.nlm.nih.gov/pubmed/26967250
http://dx.doi.org/10.18632/oncotarget.7966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991465/
https://www.ncbi.nlm.nih.gov/pubmed/26967250
http://dx.doi.org/10.18632/oncotarget.7966

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