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The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma

Abnormal expression of the clock gene PER1 is highly correlated with carcinogenesis and the development of malignant tumors. Here, we designed short hairpin RNAs (shRNAs) to effectively knock down PER1 in SCC15 human oral squamous cell carcinoma cells. shRNA-mediated PER1 knockdown promoted SCC15 ce...

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Detalles Bibliográficos
Autores principales: Li, Han-Xue, Fu, Xiao-Juan, Yang, Kai, Chen, Dan, Tang, Hong, Zhao, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991476/
https://www.ncbi.nlm.nih.gov/pubmed/26943040
http://dx.doi.org/10.18632/oncotarget.7827