Cargando…

Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma

In glioma, microglia and macrophages are the largest population of tumor-infiltrating cells, referred to as glioma associated macrophages (GAMs). Herein, we sought to determine the role of Suppressor of Cytokine Signaling 3 (SOCS3), a negative regulator of Signal Transducer and Activator of Transcri...

Descripción completa

Detalles Bibliográficos
Autores principales: McFarland, Braden C., Marks, Margaret P., Rowse, Amber L., Fehling, Samuel C., Gerigk, Magda, Qin, Hongwei, Benveniste, Etty N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991480/
https://www.ncbi.nlm.nih.gov/pubmed/26967393
http://dx.doi.org/10.18632/oncotarget.7992